Hey,
Before editing you can see your homepage?
If your database is configured correctly, and you edit it, Wordpress writes those edits on the database and they are loaded upon accessing the page. That is the way it works.
Do you use any Visual Builder? Like Visual Composer or similar? If so, you could be running into a max_input_vars problem, so you need to edit the php.ini file to increase the number (put 5000 or more). It is a safety config, so the php only pass a limited number of variables to the database, it mitigates the issue with high loads of data being transfered, so your database and php processes don’t struggle.
If you’re able to, export your Local by Flywheel logs (How do I retrieve Local’s log file?) and PHP logs (they are located in Local Sites/site_folder/logs/php/php_version_folder/error.log) and upload them here so we can take a look 