Reported that connect() failed - Connection refused

One of my sites that worked great up until today is now refusing to load. I get the error:

2020/05/01 08:30:19 [error] 54234#0: *5 kevent() reported that connect() failed (61: Connection refused) while connecting to upstream, client: 127.0.0.1, server: edunia.local, request: “GET /favicon.ico HTTP/2.0”, upstream: “http://127.0.0.1:10044/favicon.ico”, host: “edunia.local”, referrer: “https://edunia.local/?cache-buster=92

2020/05/01 08:57:34 [error] 54940#0: *4 kevent() reported that connect() failed (61: Connection refused) while connecting to upstream, client: ::1, server: edunia.local, request: “GET /?cache-buster=1175 HTTP/1.1”, upstream: “http://127.0.0.1:10052/?cache-buster=1175”, host: “edunia.local”

I’m running Local 5.3.3+3248 on Mac
Any ideas with this?

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